Penn Highlands DuBois Marks Major Milestone in Blood Clot Treatment

August 13, 2025

Author: Penn Highlands Healthcare

Penn Highlands DuBois recently marked a major milestone — 200 patients treated for Venous Thromboembolism (VTE) — a significant achievement in the fight against a potentially life-threatening condition that affects more than 1 million Americans each year.

VTE occurs when blood clots form in the deep veins of the body, most commonly in the legs or arms. When these clots develop in the legs, the condition is known as Deep Vein Thrombosis (DVT). DVT can cause leg pain, swelling, redness, and—if untreated—can lead to post-thrombotic syndrome, resulting in long-term complications.

“Clots can form for a variety of reasons, including prolonged immobility such as long-distance travel or recovery after surgery,” said Stephen Iorfido, DO, a board-certified interventional radiologist at Penn Highlands DuBois. “Risk factors include smoking, certain medications like contraceptive pills, and underlying medical conditions like cancer.”

If a DVT is not addressed, the clot can travel to the lungs, causing a Pulmonary Embolism (PE)—a dangerous and potentially fatal complication. PE can result in shortness of breath, chest pain, elevated heart rate, fainting, and sudden changes in blood pressure. Alarmingly, PE is the third leading cause of cardiovascular death, behind heart attack and stroke, claiming the lives of approximately 180,000 people in the U.S. each year.

The Interventional Radiology Team at Penn Highlands DuBois has been at the forefront of advanced, minimally invasive treatment for VTE. Using the FlowTriever Thrombectomy System, the team safely removes blood clots from the lungs of patients with intermediate- and high-risk PE without the need for thrombolytic drugs. The procedure involves guiding a catheter through the groin directly to the lungs, where clots are aspirated and removed – frequently providing immediate symptom relief.

For patients with DVT, the ClotTriever device is used to extract clots from the legs with similar effectiveness. Patients typically experience prompt pain and swelling relief. They often are able to return home in one to two days.

This milestone reflects not only the team’s clinical excellence but also their unwavering commitment to improving patient outcomes across the region.

The Interventional Radiology Team at Penn Highlands Healthcare provides advanced treatments for many conditions such as vascular diseases, cancer, men’s health and women’s health. To learn more, visit www.phhealthcare.org/interventionalradiology/.

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Penn Highlands Healthcare was officially formed in 2011 and is comprised of nine hospitals. Penn Highlands Brookville, Penn Highlands Clearfield, Penn Highlands Connellsville, Penn Highlands DuBois, Penn Highlands Elk, Penn Highlands Huntingdon, Penn Highlands Mon Valley, Penn Highlands Tyrone have served area communities for the past 100+ years. Penn Highlands State College is a new state-of-the-art hospital that opened in 2024. The health system’s business continuum also includes a home care agency, long-term care facilities and residential senior living communities, as well as durable medical equipment companies and retail pharmacies.

Penn Highlands Healthcare has evolved into an organization with approximately 6,200 employees in 150+ locations throughout 26 counties in Pennsylvania that include community medical buildings, outpatient facilities, surgery centers and physician practices. The facilities have a total of 1,396 inpatient, skilled nursing and personal care beds. The system, which has 849 physicians and 427 advanced practice providers on staff, offers a wide range of care and treatments with specialty units for cancer, cardiovascular/thoracic, neurosurgery, pulmonology, neonatal and high-risk pregnancy patients. Being focused on what is important – patients and families – makes Penn Highlands Healthcare a great choice for healthcare in the region.